glutathione biology definition Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Glutathione English | DOCX
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In response to oxidants, cysteine modification on Keap1 releases NE2FL2, which is then stabilized and transported to the nucleus where it activates transcription of antioxidant genes, including proteasomal PA28

The potential for redundancy between different enzyme classes is evident

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