oral semaglutide cardiovascular outcomes soul trial results 2024 2025 SELECT Cardiovascular Outcomes Associated with Semaglutide

Gastrointestinal discomforts (early satiety, abdominal distension, and nausea) were noted shortly after semaglutide injection

Research scenario Better conceptual fit Reason Testing GLP-1 plus satiety-pathway extension CagriSema Combines semaglutide with amylin analog activity Testing maximum receptor breadth Retatrutide Activates GIP, GLP-1, and glucagon receptors Studying diabetes plus obesity together Both Both have programs relevant to T2D and weight Comparing incremental vs radical next-gen strategy Both CagriSema extends GLP-1

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