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Creatine kinase assay The EnzyChrom Creatine Kinase Assay Kit (BioAssay Systems) was applied to measure activity in mouse brain mitochondria (as above)
therefore, if it is damaged, it can in turn increase the production of ROS and lead to more oxidative stress [4,53]
Given the relatively poor response to anti-HER2-targeted therapy in breast cancer patients with HER2 heterogeneity, the treatment regimens can be deescalated or escalated according to the HER2 status
doi: 10.1074/jbc.M209033200 45 PerrottaFScialoFMallardoMSignorielloGDAgnanoVBiancoAet al
