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High pH fractionation- TMT labeled, combined, and dried samples were resuspended in 300 L of Buffer A (5% v/v MeCN, 95% v/v H 2 O, 0.1% v/v formic acid) and fractionated by centrifugation using a peptide desalting column (Pierce, #89852)

It provides defense against cognitive impairment, acetylcholinesterase activity, oxidative stress, and cytoarchitectural abnormalities caused by aluminum chloride, in addition to potentially improving ASD symptoms by increasing GABA production [156]

Moncada, A.H

The mouse and human LTC 4 synthases have been characterized (Sderstrm et al., 1988)