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In times of high technology medicine and economic appraisal of health care this is a small cost indeed to save a life

The long latent period between the injection of a potential carcinogen and the appearance of a tumor makes it impossible to measure accurately the risk in man

doi: 10.1126/scitranslmed.aau7356

Patients show symptoms well above this mark, as B12 depletion appears in the cerebrospinal fluid even when blood levels are as high as 550
