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Description
a lack of robust randomized controlled trial (RCT) evidence, with many observational studies being of poor quality, was described
The LL extract significantly inhibited the production of NO, PGE2, IL-6, and TNF- in LPS-stimulated cells and suppressed the expression of iNOS and COX-2

Peaks at 24-72 hours, with benefits lasting post-fast

Caroprese et al., 2013)