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[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Zannis VI, Karathanasis SK, Keutmann HT, Goldberger G, Breslow JL: Intracellular and extracellular processing of human apolipoprotein A-I: secreted apolipoprotein A-I isoprotein 2 is a propeptide

2019) Microarray analysis on rat hepatocytes treated in the presence or absence of pathophysiologic levels of TMAO showed that TMAO selectively induced the PERK pathway of the unfolded protein response (UPR) without upregulation of the inositol-requiring enzyme type 1 (IRE1) or activating transcription factor 6 (ATF6) pathways

5C) when compared to control rats (Fig

Nonetheless, exosomes hold great promise as targeted delivery systems for cancer treatment and other therapeutic applications in nanomedicine