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Nonetheless, these findings collectively underscore the potential of phytobiotics to enhance gut barrier function through multiple mechanisms, including the regulation of TJPs, modulation of gut hormone expression, and reduction of serum endotoxin levels, as illustrated in Fig

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Of note, XKR8 KO neutrophils failed to form NETs in response to various stimuli in vitro, including PMA, calcium ionophore A23187, lipopolysaccharides (LPS), nigericin, monosodium urate (MSU) crystals and zymosan

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