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Early 1 HMRS work found that patients with early psychosis who used cannabis exhibited lower prefrontal Glu concentrations than both nonusing psychosis patients and healthy controls, along with a steeper age-related Glu decline, suggesting that cannabis may exacerbate glutamatergic dysfunction and influence disease progression [63]
doi: 10.1186/s13041-017-0325-8 143 OrrA.LaiP.LobinaC.MaccioniP.PirasP.et al
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