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Damiola F., Le Minh N., Preitner N., Kornmann B., FleuryOlela F., and Schibler U., Restricted Feeding Uncouples Circadian Oscillators in Peripheral Tissues From the central Pacemaker in the Suprachiasmatic Nucleus, Genes & Development 14, no

Since enzymes are one of the main costs in cell-free production, finding the minimum enzyme needed for the maximum production will make the pathway substantially efficient