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10.1186/s40880-015-0043-5 Chin
doi:10.1186/s12903-016-0215-y
doi:10.1371/journal.pone.0135268
Clinically meaningful responses in insulin-resistant patients typically include a reduction in fasting insulin of 20-40% and an improvement in HOMA-IR within 8-12 weeks at therapeutic doses, though individual variability is wide [1]
