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Moreover, it has been suggested that NF-B activation was induced by NADPH oxidase-mediated formation of ROS 35

10.3390/nu12113380 [DOI] [PMC free article] [PubMed] [Google Scholar] 59.Rodionov D, Arzamasov A, Khoroshkin M, Iablokov S, Leyn S, Peterson S, et al

56 Studies have also validated the role of neutrophils in the pathophysiology of APAP hepatotoxicity and the release of IL-1, which is produced when caspase-1 cleaves pro-IL-1
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