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Abstract Introduction and methods: As a crucial antioxidant enzyme, catalase (CAT) could destroy the cellular hydrogen peroxide to mitigate oxidative stress

This procedure allowed complete removal of all side chain protections including the side chain Pbf of Arg 32

in macrophages this axis can constrain inflammatory glycolysis and inflammasome activity, whereas in T cells it supports mitochondrial fitness and persistenceprocesses that appear perturbed after major surgery ( Beta-hydroxybutyrate (BHB), a ketone body, is another interesting example BHB directly inhibits the NLRP3 inflammasome by preventing K + efflux and possibly via activation of the hydroxycarboxylic acid receptor 2 (HCA2) on immune cells (121, 122)

This metabolite is subsequently funneled into the deoxyxylulose 5-phosphate (DXP)-dependent pathway for the synthesis of B6 vitamers 29