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As discussed earlier, senolytics focus on clearing senescent cells, while senomorphics aim to modify the SASP and other senescence-related pathways

Some individuals may require injections weekly or monthly, while others may need them less frequently to maintain adequate B12 levels

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CYP isoforms not only metabolize many endogenous substances including prostaglandins, lipids, fatty acids, and steroid hormones but also metabolize (detoxify) exogenous substances including drugs Major CYP isoforms responsible for drug metabolism include: CYP3A4, CYP2D6, CYP2C9, CYP2C19, CYP1A2, CYP2E1 in in certain cases CYP2A6 and CYP2D6 Important enzymes for phase II reactions include: Glutathione-S-transferases UDP-glucuronosyl transferases Sulfotransferases N-acetyltransferases Methyltransferases and Acyltransferases