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Concurrently, activation of the Nrf2GSH axis enhances the cellular antioxidant capacity, enabling tumor cells to maintain redox homeostasis under targeted therapyinduced oxidative stress, thus facilitating metabolic escape [77]

10.1016/j.cbi.2020.109085 98 TsengH.-H.ChenY.-Z.ChouN.-H.ChenY.-C.WuC

Hodges DM, DeLong JM, Forney CF, Prange RK

NO S-Nitrosylates NADPH oxidase Respiratory burst oxidase homolog D (AtRBOHD) at Cys890 which blunts its function in ROS synthesis (Yun et al., 2011
