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Glutathione is a vital antioxidant made by the body that supports detoxification, strengthens immunity, and defends against oxidative stress

Glutathione reductase (GR), an NADPH-dependent enzyme, continuously regenerates reduced glutathione (GSH) from its oxidized form (GSSG), thereby maintaining the intracellular reducing environment required for effective antioxidant defense, proper enzymatic activity, and redox-dependent signaling pathways [36]

Patients with a large residual urinary volume and/or severely diminished urinary flow may not be good candidates for 5-alpha-reductase inhibitor therapy and should be carefully monitored for urinary tract obstruction