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The IL-4/IL-13-STAT6-SPDEF pathway drives the Th2 response and goblet cell differentiation (93, 194)

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The following table highlights the mechanism of action of various non-enzymatic antioxidants included in infertility supplements as well as their impact on semen parameters ( Numerous studies have attempted to determine whether antioxidant therapy would improve the characteristics of the sperm and, as a result, increase male fertility

200 Overall, cathelicidins are key regulators of the inflammatory response associated with wound healing, with multiple studies supporting their immunomodulatory actions over their antimicrobial ones