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Aseptic protection: Operators must wear aseptic protective clothing and strictly follow aseptic operation procedures to prevent microbial contamination

A future national study could provide more solid evidence
Graves DT, Oates T, Garlet GP (2011) Review of osteoimmunology and the host response in endodontic and periodontal lesions

Changes in other aspects of cellular integrity can increase or decrease both the sensitivity and selectivity of screening methods used for cytotoxicity studies