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Namely, an increase in heme oxygenase 1 (HO-1) activity in breast cancer cells leads to a transient release of free iron and a consequent increase in ROS content, promoting the expression of matrix metalloproteinase 1 and cell migration [76]
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If your skin is prone to flare-ups, we recommend showering with cold water
doi: 10.1096/fj.09-132795
