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As a result, this group and the control group were identical (SI = 100.00%
however, the upregulated genes in malignant cells were enriched in cellular senescence, RNA degradation, thermogenesis, spliceosome, and ubiquitin-mediated proteolysis, suggesting that in malignant cells, the activities of RNA degradation and splicing are significantly increased, and ubiquitin-mediated proteolysis is increased, which reflects the cellular response to malignant transformation
(6) Complex I: Complex I (NADH:ubiquinone oxidoreductase) is a large multiprotein complex located in the mitochondrial inner membrane that accepts electrons from NADH and transfers them to ubiquinone (CoQ 10 ) via FMN and a series of ironsulfur (FeS) clusters, reducing it to ubiquinol (CoQ 10 H 2 ) 68,69
This is an educational research reference, not medical advice or a dosing recommendation
