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BRASS et al, 1994, VUKOVICH et al, 1994
Use of AI can be particularly beneficial with rare diseases or targeted therapies, where profitability of a clinical trial is less certain [319]
66 In contrast, pharmacologic inhibition of FAO with etomoxir or ranolazine inhibited cancer cell proliferation and sensitized human leukemia cells to apoptosis induced by ABT-737, a molecule that released proapoptotic Bcl-2 proteins such as Bak from antiapoptotic family members, suggesting that CTP1 can antagonize Bcl-2-induced apoptosis
