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At pH 3.88 (acetate form), accelerated stability testing shows degradation to 21.3% remaining after extended heat stress, while at pH 8.42 (sodium salt), 96.7% remains under identical conditions
A dose of 20 ppm results in improved oxygenation and the most optimal decrease in pulmonary to systemic arterial pressure ratio (69) and is the typical starting dose
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Genome Res 20 , 93846 (2010)
