l-carnitine deficiency causes Primary systemic carnitine Carnitine: Genetic Variants Affecting Mitochondrial

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In a recent double-blind, randomized, placebo-controlled trial, the effect of ALCAR was examined in 229 participants treated for type 2 diabetes mellitus, hypertension, and dyslipidemia (46)

Conversely, no variants were found on the SLC25A20 gene, whose mutations are associated with the carnitine-acylcarnitine translocase (CACT) deficiency (MIM 212,138), which is as well a rare autosomal recessive disorder of long-chain fatty acid oxidation [7]

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