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7.5 Challenges and controversies in researching the gut-brain-metabolic axis Despite the promising findings regarding the role of gut microbiota in regulating insulin resistance and cognitive function, several challenges and controversies remain in this field: 7.5.1 Variability in microbiota composition Individual variations in gut microbiota composition can lead to inconsistent results across studies

We utilized thioflavin T stain and fluorescence microscopy to visualize microclot formation and quantified the results using Image-J software

The dimer then binds to specific response elements, resulting in transcriptional activation of genes regulating P450 expression (Liang et al

doi: 10.3322/caac.21763
