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Efficacy and safety of sonothrombolysis in patients with acute ischemic stroke: A systematic review and meta-analysis
Chronic stress activates sympathetic nervous system responses, elevates cortisol, and creates mental hyperarousal that interferes with sleep onset and maintenancewhile poor sleep quality impairs stress resilience, reduces emotional regulation capacity, and increases vulnerability to anxiety
their activation inhibits presynaptic calcium influx and suppresses the release of excitatory neurotransmitters such as glutamate and substance P, thereby reducing central sensitization [343]
Mihalko Gary D
