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The presence of Au-NPs in the gold nano-extract, known for its anti-inflammatory properties, normalized mRNA levels of inflammation markers and antioxidant enzymes, modulating the biological response at a molecular level by reducing inflammatory gene expression and increasing antioxidant gene expression 116

A safety review in the Journal of Obesity & Food Metabolism describes six randomized, double-blind, placebo-controlled trials evaluating AOD-9604, including oral dosing studies and longer phase II programs

doi: 10.1590/s0004-27302007000800027

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