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Astrocytic endfeet contribute to the regulation of microvessel dilation and constriction, thereby exerting control over blood flow [47, 48], underscoring the dependence of the glymphatic system functioning on the optimal functioning of astrocytes [49, 50]

INDICATION ONYDA XR (clonidine HCI) is a centrally acting alpha2-adrenergic agonist indicated for the treatment of attention deficit hyperactivity disorder (ADHD) as monotherapy or as adjunctive therapy to central nervous system (CNS) stimulant medications in pediatric patients 6 years of age and older

Hashimoto S, Yatsuhashi H, Abiru S, Yamasaki K, Komori A, Nagaoka S, Saeki A, Uchida S, Bekki S, Kugiyama Y, et al

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