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the rest microbiome members lacking the ability, however, are consumers (folate auxotrophs) and rely on those folate producers to provide folate, which may limit the vitamin availability for the host including humans 248,250,251,252,253,254,255,256,257,258,259

Deficient IGF- 1 input to vascular endothelial cells leads to impaired vasodilation, microvascular rarefaction, and reduced muscle endurance, without significant muscle atrophy

They found that curcumin treatment led to the re-expression of DLEC1 in HT29 colon cancer cells

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