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Mechanistic basis of ischemiareperfusion injury and classical and novel molecular pathways of cardioprotection Main mechanisms of myocardial IRI IRI results primarily from a complex interplay of metabolic, ionic, and oxidative disturbances that occur during ischemia and upon restoration of blood flow [79]

We also tested the sodA and spxB mutants that have previously shown a lower phenotype than wt [6, 32], although these strains displayed a higher H 2 O 2 resistance than the mentioned mutants, but significantly lower compared with the wt strain (Fig 3B, Fig S2)

J Biol Chem 291(23):1218412194

Insulin-like growth-factor-binding protein gene expression and protein production by human tumour cell lines