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PMID 27550381

It is evident that CUR can promote bone formation and inhibit bone resorption through the regulation of the Wnt/catenin signaling pathway ( 4.2 Regulation of NF-B signaling pathway by curcumin in osteoporosis In conclusion, curcumin shows promise in the therapeutic management of osteoporosis (OP) by targeting the regulation of the NF-B/IL-6 signalling pathway, a mechanism that significantly inhibits inflammatory processes (Yang et al., 2023a)

Vande Velde, F., Burhenne, J., & Haefeli, W

Gene set enrichment analysis (GSEA) was performed using the fgsea R package on the ontology gene sets retrieved from gsea-msigdb.org ( An FDR threshold of 0.1 was implemented