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Aminoacids (like serine) are major one-carbon sources, and cancer cells are particularly susceptible to the deprivation of one-carbon units by serine restriction or inhibition of de novo serine synthesis

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Acetyl-CoA, which is a metabolic substrate, enters the tricarboxylic acid (TCA) cycle to help maintain mitochondrial oxidation

The maximum level of folate biofortification reached in rice seeds exceeds the recommended daily allowance for an adult person (400 g) more than fourfold