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These pathways and cell groups form a dopamine system which is neuromodulatory

This phase is androgen-dependent and may be impaired in androgen receptor defects [48,49,50] or inborn error of steroidogenesis [23], although causative mutations are rarely identified in isolated cases [51,52,53]

Gastric bypass surgery : This surgery alters the digestive system, reducing the bodys ability to absorb B12 from food and supplements.For these individuals, methylcobalamin B12 injections provide a direct way to bypass the digestive system and restore essential B12 levels

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