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GRX1 deficiency exacerbates COPD progression by elevating TGF- levels, collagen deposition and basal cell plasticity, accelerating lung remodeling (87)

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KDM6A encodes a lysinespecific demethylase that demethylates lysine 27 of histone H3 (H3K27) to promote gene expression

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Oxidative stress can arise from various sources, including mitochondrial dysfunction, impaired autophagy, lipid peroxidation, misfolded proteins and cytosolic ROS-producing enzymes

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Monitor for any signs of discomfort

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