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Description
GRX1 deficiency exacerbates COPD progression by elevating TGF- levels, collagen deposition and basal cell plasticity, accelerating lung remodeling (87)

KDM6A encodes a lysinespecific demethylase that demethylates lysine 27 of histone H3 (H3K27) to promote gene expression
Oxidative stress can arise from various sources, including mitochondrial dysfunction, impaired autophagy, lipid peroxidation, misfolded proteins and cytosolic ROS-producing enzymes
Monitor for any signs of discomfort
