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10.1016/j.phrs.2022.106163 97 NyawoT

Sim JH, Park YL, Lee JS, et al

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While fusion is generally thought to be protective in times of stress by allowing content mixing and sharing of healthy mitochondria to counteract damage to others, it has also been shown to increase the spread of detrimental mtDNA in a model of sepsis, suggesting it may exacerbate certain inflammatory conditions