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Description
Together, these findings underscore that sarcopenia transcends a mere muscular ailment and manifests as a systemic vascularmetabolic syndrome, wherein endothelial dysfunction and mitochondrial deterioration serve as converging mechanisms
Because the cells are trapped in this inefficient metabolic state, they rapidly burn through their available glucose while generating a fraction of the necessary energy, further compounding the deep cellular exhaustion
For example, blocking amino acid metabolism in T cells can decrease the incidence of AIH
10.1016/j.pcl.2020.12.011 Alexandra L
