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Description
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C.KoeppeM

Metabolism and Pharmacokinetics (Panel 2) : The drug operates with a rapid 3 to 5 minute half-life, which translates to a short clinical duration of approximately 6 to 10 minutes

Evaluating the protein structural context of affected residues using the three-dimensional structure of recombinant human tetrameric PK has provided a rationale for the observed enzyme deficiency and contributes to a better understanding of the genotype-to-phenotype correlation in PK deficiency
