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Description
GPX4 in disease Impaired GPX4 activity is often positively associated with increased oxidative stress and RCD in disease

4-Hydroxythalidomide based PROTACs By exploiting the reactivity of the phenolic group of 4-hydroxythalidomide, its direct alkylation allows the synthesis of diverse and versatile starting building blocks for subsequent incorporation into the construction of cereblon-based PROTACs, e.g., via amidation, alkylation or click-chemistry reactions 97,110,111,112

Many papers reported the IRI tissue damage in VCA
doi: 10.3390/md21090475