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2023;18 doi: 10.1371/journal.pone.0285523

Continuous data collected from the participants over the 26 week treatment period was assessed using an ANCOVA model, using randomized treatment as a factor and baseline bodyweight as a covariate

However, the effect of C677T polymorphisms of MTHFR on cognitive function was not significant in normal subjects as a longitudinal cognitive study showed that the MTHFR C677T polymorphism was not associated with cognitive performance at baseline or over 12 years 49

We hope to provide a comprehensive assessment of PEAKS Online performance on PTMs in a future study
