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Measurement of intracellular and cell supernatant H 2 O 2 levels For intracellular and cell supernatant H 2 O 2 levels, 143B cells were plated in 6-well plates
ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail
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Current GLP-1 therapies (Ozempic/semaglutide, dulaglutide, liraglutide) require: Refrigeration and cold-chain storage Subcutaneous injections (compliance issues) Complex, expensive manufacturing Restrictive dosing (oral semaglutide: overnight fasting, 30-min wait before eating) All prior candidates failed due to poor potency or inadequate pharmacokinetics ( 3,100 adults with obesity (without diabetes)
