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Description
Subcutaneous administration appears most common in published protocols, though intramuscular, intraperitoneal (in animal models), and even oral routes have demonstrated efficacy
It can affect its 3D shape, stability against enzymes, ability to bind to cellular receptors, and its overall biological activity
Detailed plasma pharmacokinetics and absolute oral bioavailability in rodents are still being characterized in the open literature
Setton J, Lee NY, Riaz N, Huang SH, Waldron J, O'Sullivan B, Zhang Z, Shi W, Rosenthal DI , Hutcheson KA, Garden AS
