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Intact Dihexa has been retrieved in cerebrospinal fluid samples taken from rats following both oral and parenteral treatment (data in preparation for publication)
Mechanisms proposed include activation of focal adhesion kinasepaxillin pathways, stimulation of growth factor signaling, and support for nitric oxidemediated vascular responses
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151 If without further engineering, the ability of terpolymer III-62% to penetrate the BBB is limited
