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Description
This might have resulted in an insufficient return to the threshold, as in the present study

After binding to the tyrosine kinase PDGF receptor (PDGFR), it affects the chemotaxis and proliferation of fibroblasts (Gervaz et al., 2009)

Dosage plays a role

There are four phases of first-in-human clinical trials, and the drug candidates are generally approved after the third phase if they are found safe and effective
