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It is likely that this milieu of combined glutathione and cysteine depletion develops in some patients who chronically ingest acetaminophen, especially if their intake of cysteine precursors, such as methionine, is deficient

doi: 10.1136/bmjopen-2020-047069 232 TelakuS.TelakuM.BehluliE.IsjanovskiV.AlidemaF

We consider that a single loading dose of secukinumab failed to effectively control the cytokine storm, leading to disease progression
