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Nat Med 24:15261531

These enzymes play a role in maintaining redox cycling during the many metabolic reactions activated upon T cell receptor (TCR) stimulation ( + at the plasma membrane ( The endoplasmic reticulum (ER) also contributes to ROS production in T cells ( 2+ ) signalling upon TCR stimulation ( Finally, a recurring theme in this review is amino acid deprivation as a stimulator of ROS accumulation

PLoS ONE 11 , e0149679 (2016)

They are used to study urate-induced cartilage degradation and autophagy abnormalities
