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It is conceivable that in ASD, neuronal hyperexcitationconsistent with the excitatory-inhibitory imbalance hypothesistriggers compensatory excessive inhibition in specific brain regions, which may be reflected by elevated GABA concentrations

Activation of the PPP has also been demonstrated in cancer cells, probably to produce more NADPH to combat oxidative stress [230]

Embryonic day (E)18 embryos were obtained by cesarean section of pregnant females from timed mating of heterozygous mice

CD38: an immunomodulatory molecule in inflammation and autoimmunity