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doi: 10.1016/j.ajg.2019.05.004 276 LeeJWParkSH

The inhibition of autophagy may allow an imbalance in NRF 2 -mediated metabolism as well as redox regulation, which increases iron deposition and lipid peroxidation, promoting cardiomyocyte ferroptosis and the progression of T1DM cardiomyopathy (79)

Fractionation of these plasma samples by size exclusion chromatography showed that treatment-induced increases in immunoactive GH was associated with molecular forms in mass ranges expected for dimeric (3060 kDa) and monomeric ( 60 kDa) molecular mass variants contained form(s) that were equally as potent as the small (30 kDa) and medium (3060 kDa) class fractions in terms of generating a bone growth response