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For other cells in the TME, inhibitory immature myeloid cells (IMCs), well-known immunosuppressive cells, enhance glycolysis in the tumor microenvironment and can perform normal inhibitory functions in low-sugar environments due to glutamine metabolism (62)
[PubMed] Brzoska T, Luger TA, Maaser C, Abels C, Bhm M
An alternative substrate appears to be responsible for the residual insulin/IGF-1 action
Huang Y, Wang Q, Gao J, et al
