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Description
Knockout of either Grx5 or Grx3 leads to iron accumulation in cells [31,136,137] , impaired FeS cluster biosynthesis [138] , and deregulated iron homeostasis via IRPs [31,137,139] (Figure 4)

Introduction Tuberculosis (TB) accounts for one of the top 10 causes of mortality from a single infectious agent

This effect has been observed by other investigators (Seung-Jae Lee, Alex Mendenhall, personal communication)

Serum concentrations of urea, creatinine, and uric acid were quantified using commercial assay kits (Urea: ab83362, Abcam, USA
