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In addition, dysregulated -KG flux from normal reductive anabolism via the TCA cycle toward R-2-HG production has been associated with other metabolic flux impairments and disrupted redox balance 119,120 (Fig
doi: 10.3389/fphar.2019.00376 103 LiX.-J.ShanQ.-Y.WuX.MiaoH.ZhaoY.-Y
But as mentioned, there's evidence to show that high oral doses of vitamin B12 can be just as effective at treating a deficiency
