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Research confirms heatstroke is linked to long-term organ problems and increased vulnerability to future heat illness

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Circulating monocytes from RA patients produce elevated levels of IL-1 and IL-6 upon in vitro stimulation (69), IL-6 contributes to joint destruction (70), while IL-1 promotes osteoclastogenesis, induces matrix metalloproteinase (MMP) expression in chondrocytes, and initiates synoviocyte proliferation (71)

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